Rehab LLMs: What To Map, Conceptually, for Depression—and Addiction

What is the human mind? Early options are genes and neurons. Genes are established to be the architects of human existence.

The human genome has already been mapped, in full. However, there are other options that structure nurture functions aside from genes. For example, an offspring has the genes of the parents, but the language that the offspring would speak may depend on another factor. Simply, the capacity for language is possible by genes, but the language content is organized by another factor. Language is directly a function of the mind, just like several others, ruling out genes as the human mind—with this example, though others like subjects at school, neuroplasticity and so forth also rule out genes as the human mind—conceptually. Genes often make calls–or act as engines—when expressed, but the wheels of functions are different.

Neurons in several parts of the human brain have been mapped. There is a field called connectomics dedicated to this science. So far, with advances in neuroscience, there has never been a neuron that has been identified for language, math, or others. Neurons are known to be active during functions. But if neurons were the human mind, it would mean that they change in a certain way for a function, and then others in another way. Simply, for different aspects of language, or subjects, or smells, some neurons would be something, different from others. Then neurons for smell may also be different from neurons for touch. There have not been neural differences, observed from neuroimaging and connectomics, to indicate that neurons are changing much or that their anatomy is responsible for a function or functions, directly.

So, if genes and neurons are not the human mind, what might the human mind be? Also, if what the human mind is, is theorized, how does it work, what is order in the mind, what is disorder? What happens in the mind that results in the experience of depression—and addiction?

Human Mind

The human mind is theorized to be the collection of all the electrical and chemical signals, in sets, with their interactions and features, in clusters of neurons across the central and peripheral nervous systems.

Electrical and chemical signals have to interact in sets, to determine functions. Electrical and chemical signals have their features that determine the measures for those interactions

Interactions are principally the strikes of electrical signals on chemical signals, in sets. Features include prioritization, pre-prioritization, splits, old sequences, new sequences, principal spot, arrays, thick sets, thin sets, intensity and so on.

A few of these can be theorized to be responsible for depression.

Read More: Conceptual Descriptions of the Human Mind on Sedona.biz I

 Possible Components of Depression

It is theorized that depression is a problem of the principal spot, which is a prioritization segment of sets of signals. Prioritization is defined as the set of chemical signals with the most volumes among all in any instance. This means that when a set has the most volume among all, it becomes prioritized. It is prioritization that defines what is labeled as attention. Other sets are pre-prioritized. There are often fast and numerous interchanges between pre-prioritized sets and the prioritized set.

The prioritized set often has a distribution veto—in the prioritized instance. This means that it can distribute summaries of its configuration, to several other sets of signals, in that instance. The prioritized set also has a high totalization index, which means that the set of electrical signals can interact with the full spectrum of the set,  making it possible to access its functions. It is prioritization that makes listening different from hearing, or many instances or main vision different from other instances of peripheral vision [although main vision can be pre-prioritized, but may be in the array, to be prioritized again].

The sets of signals with volumes that may be prioritized are often in an array. This means that recently prioritized or those that are likely to be prioritized are often arrayed, such that they can switch and then distribute, then switch again multiple times. It is the interchanges between prioritization and pre-prioritization that makes it possible to do several tasks at the same time, like driving, speaking, listening to music and so forth. Prioritization is also useful in the mind, not for where to focus attention or what to change, so that there is a urgency to reduce it.

Beyond prioritization is what is called the principal spot, it means the set of signals with the most domination. This means that it is not just attention, or the ability to be in the array, but to lead the array, determine distributions, have totalized interactions and be there for some time. This principal spot is not necessarily a physical location, but a chemical signal configuration that keeps the maximum volume nearly constant, such that displacing it may become less frequent than regular prioritization.

There are sets of signals for everything. All experiences are configurations of sets of signals—conceptually. There is a set of signals for emptiness. There is another for fatigue. There is a set of signals for pleasure, and another for a smell, a taste and so forth.

Chemical signals hold these configurations, but electrical signals have to interact with them to access the configurations. There are several prioritization categories, but two of them include prioritization counterbalances and prioritization continuity. Counterbalance may be explained with [say] being thirsty and drinking water, such that the new prioritization cancels the old one. Although the old one may [try to] persist in some cases, if the new one is sufficient enough the old one goes away. There are several other examples of prioritization like when a demand is canceled out by the supply, even if the [say] element [water or food] is yet to be absorbed by the body—so to speak.

Prioritization continuity is the situation where prioritization continues to build in a set, such that if there is no pause or break, it keeps going, not allowing other functions to get prioritized, while possibly over-using that function, which may cause issues in other sets that do not get prioritized, or even in the set, by over-using the volumes that are possible. Simply, there are sets where the prioritization may not change and would keep going without a break. An example could be muscle use in one direction for a long time, or heat strokes, or severe cold. While some sets of signals may, in a prioritized situation, switch to something else in pre-prioritization, giving some break to that set, some sets would just keep going, until it breaks in some problematic way.

This means that [say] music is within earshot during some experiences [or say prioritization of some sets] it is possible that switches between the sets for the music and those of the experience would ensure that the experience has prioritization breaks, but some sets may not allow—and keep going. Sometimes, this continuance is a result of the principal spot.

There are sets of signals that are for experiences of nothing or regular, such that they are not just prioritized after say, thirst, but can also be prioritized in cases of just normality.

Read More: Conceptual Descriptions of the Human Mind on Sedona.biz II

Depression

Depression is theorized to be a set of signals for nothingness moving to the principal spot, allowing it to lead the array of distribution and dominate against anything else that is pre-prioritized or prioritized. Simply, depression is a state where a set of signals that is supposed to be a neutral set, moves into the principal spot, then gives out distributions of the summaries of its configurations, which [then] becomes how some other sets that should not normally get the distributions do so.

For example, the set responsible for excitement or [say] pleasure may instead get distributions from the set of ‘neutral’, or the set for satisfaction from something may get the same. There can also be others like heaviness or lethargy getting distributions and becoming sometimes prioritized, since some sets of signals for lethargy and nothing may share the same thick set [a feature].

Simply, depression is theorized to be a state of the mind, where the set of signals that is supposed to be neutral becomes prioritized and moves to the principal spot, where it dominates, such that allowance for prioritization from other sets, whose prioritization may displace it, are reduced. It may also distribute to other sets like heaviness or fatigue, which may then distribute to apathy.

Depression is a set of the relays and interactions of electrical and chemical signals of the mind, which can be displayed for every symptom of the condition.

Addiction

Addiction is the movement of craving to the principal spot, which dominates arrays. Simply, craving is at the head of arrays, which distributes its configurations to other sets, making it appear like there is a general need for ‘the thing’. This is also expanded by splits of electrical signals [a feature], which after the last intake, there is an early split to the set of signal for pleasure, satisfaction or notice of taking it, but this does not get the full interaction, thereby, signaling that something is not complete, so another intake becomes desired.

Simply, after the last intake, there is a split of electrical signals, to the same destination, but without the full summary that it had been taken and then without the full interaction at the destination, which then distributes to an experience of absence, which may then move the urge for the craving.

Addiction can also be a result of depression, where there is just a continuous intake, to try to drive away the emptiness from the principal spot.

LLMs and Mind Displays

The necessity of a probabilistic way the human mind works and what occurs in a depression is to take one step away from the opacity of the states of depression—and addiction, such that knowing what might be responsible, like principal spot, arrays, prioritization, splits of signals and so forth, may become a way to shape how therapy becomes possible or what to do pre-rehab, during or post-rehab.

Large language models [LLMs] can be used to display and describe the mind, with this concept, for every symptom of depression and substance use disorder, so that it is possible to understand what it might be, and to find what might be appropriate, rather than trying different things, which may not work at all.

The goal is to ensure that progress is possible and fast enough against depression and addiction

There is a recent news in Nature, Brain stimulation at home helps to treat depression, stating that, “A remote clinical trial involving more than 150 people has shown that an experimental treatment for depression — which uses a swimming-cap-like device to gently stimulate the brain — can be effective when carried out at home. The non-invasive therapy, known as transcranial direct current stimulation (tDCS), is designed to stimulate areas of the brain linked to mood regulation, and delivers a painless, weak electrical current through electrodes placed on the scalp. It could be a game-changer for the more than one-third of people with depression who do not respond to standard treatments such as antidepressants or psychotherapy.”

There is a recent story on WSJ, Can Zapping the Brain Help Treat Addiction?, stating that, “A radical experiment uses focused ultrasound waves to reset cells inside the brain’s reward center to combat cravings.

There is a recent story on Medscape, Will Psychedelics Break the Major Depression Logjam?, stating that, “With tens of millions of euros in the offing, researchers across the European Union have eagerly taken up the gauntlet to find novel interventions for difficult-to-treat mental health and pain conditions. Their target is psychedelics, including classic compounds like psilocybin and atypical ones like ketamine and MDMA. Some of these still carry a stigma as party drugs and spiritual gateways to holotropic experiences. A total of 12 groups make up the European College of Neuropsychopharmacology’s psychedelic research network. Along with several affiliates, the groups span nine countries (Denmark, Sweden, Finland, Switzerland, Germany, the Netherlands, the Czech Republic, Greece, and the United Kingdom) and are focused on the use of psychedelic compounds as potential treatments for psychiatric conditions such as treatment-resistant depression (TRD), addiction, attention-deficit/hyperactivity disorder, anorexia, and obsessive-compulsive disorder. One of the largest endeavors is PsyPal, a 4-year, randomized controlled trial investigating the potential of psilocybin for treating psychological distress in palliative care patients with life-limiting conditions. PsyPal is the first multisite clinical trial funded by the European Union to explore psychedelic-assisted therapy.”