By David Stephen
Sedona, AZ — There are several dangerous experiences where panic, fear, or flight may result because of the possibility of death. This, conceptually, can be interpreted as relays in the mind to avoid that outcome.
It is different in some mental illnesses, where the state and constancy of the harrowing experiences distribute into wanting out, by death. Simply, the likelihood of death by suicide or overdose may not have routed through destinations of panic, fear or flight, but to the perception that calm could be accessed without regard to its irreversibility.
How does the human mind distribute information that ensures a flowing relationship with the external world and modulation of internal senses, but may sometimes direct into harm without relay for consideration of consequences?
It is possible to hear a word and another meaning is—initially—interpreted before the context or a repetition result in the right meaning. Relays are constant in the mind, across destinations, in every instance. Why are they sometimes negative? Why do some negative ones result in the prompting to act without veto by consequences or intentionality?
In a report by The NYTimes, Montana’s Suicide Rate Is Highest in the U.S., With Most Involving Guns, it was stated that, “Over the past three years, Montana’s typically elevated suicide rate was the highest in the nation, according to an analysis of federal mortality data by The New York Times. In a state of 1.1 million people, 955 people died by suicide from January 2021 through November 2023. Last year, suicides in Montana and the nation declined to near prepandemic levels. But the rate of suicides in Montana remained one of the worst in the country, and a source of widespread grief across the state. Many of these deaths are felt but not seen. Suicide, despite its frequency, can still be steeped in secrecy and shame. The deaths often come after a struggle with mental health issues or substance abuse. Nalmefene is an opioid receptor antagonist which is used to treat acute opioid overdose.”
In another report by The Philadelphia Inquirer, Philly health officials detect a veterinary sedative more powerful than xylazine in drug samples, it was stated that, “A veterinary drug similar to xylazine, medetomidine, turned up in two samples of fentanyl in Philadelphia, and a Montgomery County resident died of an overdose involving the synthetic opioid nitazene.”
In a recent press release, FDA Approves First Nalmefene Hydrochloride Auto-Injector to Reverse Opioid Overdose, stating that, “the U.S. Food and Drug Administration approved Zurnai, the first nalmefene hydrochloride auto-injector for the emergency treatment of known or suspected opioid overdose in adults and pediatric patients 12 years of age and older. The agency approved the first nasal spray formulation of nalmefene in May 2023. Drug overdose persists as a major public health issue in the U.S., with more than 107,000 reported fatal overdoses occurring in 2023, primarily driven by synthetic opioids like illicit fentanyl. Nalmefene and naloxone are two available options to reverse opioid overdose. The FDA has worked to increase availability and accessibility of both options to encourage harm reduction and reduce overdose death. If nalmefene is administered quickly, it can reverse the effects of opioid overdose, including respiratory depression, sedation and low blood pressure (hypotension). The newly approved product delivers 1.5 milligrams (mg) of nalmefene under the skin (subcutaneous) or into muscle (intramuscular). Zurnai is a single-dose, pre-filled auto-injector and is available only by prescription.”
What is the human mind? Why do some states of mind seek substances with risks of an overdose? It is postulated that the human mind is the collection of all the electrical and chemical impulses of nerve cells, with their interactions and features, in sets [in clusters of neurons across the central and peripheral nervous systems]. Electrical and chemical signals have to be directly affected for anything—glia, microglia, synapses, genes, environment, therapy, medications and others—to affect mental health.
The human mind has principal divisions or functions—memory, feelings, emotions and modulation of internal senses. These divisions have several subdivisions like pain, fear, intelligence, thoughts, delight, cravings, prompting, and so on. The divisions and subdivisions have features by which they are qualified or graded. This implies that features set functionalities per instance. Features include attention, awareness [or less than attention], self or subjectivity, and free will or intentionality.
Conceptually, sets of electrical and chemical signals bear functions and their features. There are other features too like distribution, splits, principal spots, sequences, arrays, thick and thin sets as well as others.
Distribution, splits, sequences, and principal spot may sometimes be responsible for the desire of death as an out to some mental illnesses. Depression, for example, can be said to be a state where some sets [of signals] are in the principal spot, dominating beyond regular attention and drawing power from other sets, resulting in heaviness and the lack of strength for other things. In that state, or certain others like intrusive thoughts or promptings, relays may not go to hope or consequences, but to ease, with death or serious self-harm, like an overdose, as welcomed.
This becomes dangerous when the promptings get so intense, hijacking intentionality or arrays [a qualifier that defines non-intent], then without distribution to hope or consequences, might the desire mature to seek suicide or an excess of dangerous substances.
Simply, a reason [conceptually] that some mental illnesses find suicide ideation or steep substance abuse as a choice is that some sets of [signals] are stuck at the [principal] spot and there is a lack of distribution to [sets of signals that mechanize] hope, fear or consequences.
How can the mind, for mental health or illness be measured against seeing death as an option? To fight suicide and overdoses, it will also be important to explore how sets of signals are distributed on the mind, to have a display of it, create awareness against letting harmful options linger long enough to prompt perilous action.
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5 Comments
Some of the problem is due to genetic inherited trauma. Some is due to overactive neurons caused by trauma and or excessive endorphin/adrenal flow over extended periods of time as is experienced by many GI’s and First Responders.
Buprenorphine/Butrans patches are good equalizers for some but is extremely difficult to get prescribed especially for minority and lower income populations who are most likely to need it.
thanks for the comments,
yes, genes play a role, one thing though is that when genes in neurons are to have effect [or be expressed], they often do through signals [chemical and electrical], conceptually.
From this source,
https://www.ninds.nih.gov/health-information/patient-caregiver-education/brain-basics-genes-work-brain
“At least a third of the approximately 20,000 different genes that make up the human genome are active (expressed) primarily in the brain. This is the highest proportion of genes expressed in any part of the body. These genes influence the development and function of the brain, and ultimately control how we move, think, feel, and behave. Combined with the effects of our environment, changes in these genes can also determine whether we are at risk for a particular disease and if we are, the course it might follow.”
conceptually, it is not that genes help to think or feel, directly, they do through electrical and chemical signals.
Also, when the environment has some effect on thought or behavior, they do not do so directly with the genes, they first influence the signals.
so, the thing is that to fight overdose and self-injury [fatal or otherwise], it might also be possible to explore how the signals mechanize those actions.
thanks for the comments.
https://medium.com/predict/brain-science-and-panpsychism-are-genes-the-human-mind-ac5b679daaa4
Thanks for all of that good info.
So if neuro transmitters are interrupted say via nerve agent exposure and one wishes to scratch an itch on their nose but ended up scratching their elbow instead is that not a similar response as to that of an addict wishing not to use but ultimately does?
It’s an involuntary neurological response is it not?
Excuse me for my ignorance of the more in depth explanations because obviously I am not a doctor nor scientist. Just an average bloke.
a toxicologist would probably answer this better,
anyways, there are nerve cells in the CNS and the PNS.
All that these nerve cells do involve their signals.
My exploration is how those signals configure functions.
a lot of thanks for engaging,
excellent.
Cool field of study.
I worked for the UK equivalent of the US company Raytheon for 30 years and had some exposure to the effects of chemical weapons upon the human body and its nervous system.
Again, I am not a scientist nor physician but did learn a bit about how nerve agents disrupt neurotransmissions to the point of shutting the entire system down. I found that to be both fascinating and frightening. Especially considering that common pesticides such as DEET are in essence nerve agents. I believe heavy metals can cause similar reactions in humans and animals?
Perhaps if you can reverse engineer the effects of these toxins upon the nervous system maybe it can help you to understand what you seek to know?
Just spitballing here of course.